Aprepitant
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Child cancer
Antiemetic
For use with highly emetogenic chemotherapy regimens in combination with ondansetron +/- dexamethasone (dexamethasone should be dosed at 50% due to drug interaction).
For use in children <12yrs & 40kg discuss with consultant first.
| Oral | |
| Aprepitant (Emend™) (po) dose banding: If enrolled on protocol verify drug is allowed | |
| ≥12 yo or >40 kg | 125mg day 1 and 80 mg day 2 and 3 |
| 25 kg-40 kg | 80 mg day 1, 2 and 3 |
| 15 kg-24 kg | 80 mg day 1 and 40 mg day 2 and 3 |
| <15 kg | 3mg/kg day 1 and 2mg/kg day 2 and 3 |
HML restricted.